Compound Detail
CHEMBL1761258
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Basic Information
| ChEMBL ID | CHEMBL1761258 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HJXKOPMRKLRHPC-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
253.1
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 4.33
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Beta-lactamase CHEMBL2725 | Ki | 4.33 | 4.33 | 46560.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Beta-lactamase | Ki | = | 46560.0 | nM | 4.33 | Inhibition of Enterobacter cloacae P99 beta-lactamase AmpC P99 using nitrocefin ... | 21392987 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 21392987 | 10.1016/j.bmcl.2011.02.024 | Unchecked | 3 |
| 24075731 | 10.1016/j.bmcl.2013.08.096 | PBMC | 3 |
| 21392987 | 10.1016/j.bmcl.2011.02.024 | Beta-lactamase | 1 |
Data from ChEMBL 36 via Core Engine