Compound Detail
CHEMBL1766162
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Basic Information
| ChEMBL ID | CHEMBL1766162 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RAXOCFXWDKZGML-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
285.1
MW (Da)
3.98
ALogP
3
HBA
2
HBD
49.7
PSA (Ų)
0.90
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.18
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Tyrosinase CHEMBL5346 | IC50 | 4.18 | 4.18 | 66400.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Tyrosinase | IC50 | = | 66400.0 | nM | 4.18 | Inhibition of tyrosinase activity in alpha-MSH-stimulated mouse B16 cells using ... | 21429753 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 21429753 | 10.1016/j.bmc.2011.02.044 | B16 | 2 |
| 21429753 | 10.1016/j.bmc.2011.02.044 | Radical scavenging activity | 2 |
| 21429753 | 10.1016/j.bmc.2011.02.044 | Tyrosinase | 2 |
Data from ChEMBL 36 via Core Engine