Compound Detail
CHEMBL17833
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Basic Information
| ChEMBL ID | CHEMBL17833 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JGYVZUCCBOVDJE-PKOBYXMFSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
359.4
MW (Da)
2.31
ALogP
5
HBA
3
HBD
73.2
PSA (Ų)
0.77
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 7.96
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Rattus norvegicus CHEMBL376 | IC50 | 7.96 | 7.96 | 11.0 | 1 |
| Unchecked CHEMBL612545 | IC50 | 7.46 | 7.46 | 35.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Rattus norvegicus | IC50 | = | 11.0 | nM | 7.96 | Compound was tested for neuroprotection against NMDA-Induced toxicity in culture... | 9544217 |
| Unchecked | IC50 | = | 35.0 | nM | 7.46 | Displacement of racemic [3H]CP-101606 from rat forebrain membrane N-methyl-D-asp... | 9544217 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 9544217 | 10.1021/jm9707986 | Rattus norvegicus | 3 |
| 9544217 | 10.1021/jm9707986 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine