Compound Detail
CHEMBL1807910
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Basic Information
| ChEMBL ID | CHEMBL1807910 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | KJEPOCRSGMXXNO-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
1
PK Parameters
3
Publications
0
Known Names
Molecular Properties
314.8
MW (Da)
3.67
ALogP
4
HBA
1
HBD
59.8
PSA (Ų)
0.80
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.12
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Molecular identity unknown CHEMBL612546 | EC50 | 6.12 | 6.12 | 760.0 | 1 |
Pharmacokinetic Data
| Parameter | Value | Units | Species |
|---|---|---|---|
| T1/2 | 4.85 | hr | Homo sapiens |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Molecular identity unknown | EC50 | = | 760.0 | nM | 6.12 | Upregulation of utrophin transcription in mouse H2K cells after 48 hrs by lucife... | 21741236 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 21741236 | 10.1016/j.bmcl.2011.06.047 | Molecular identity unknown | 1 |
| 21741236 | 10.1016/j.bmcl.2011.06.047 | No relevant target | 1 |
| 21741236 | 10.1016/j.bmcl.2011.06.047 | Liver microsomes | 1 |
Data from ChEMBL 36 via Core Engine