Compound Detail
CHEMBL1807918
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1807918 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BWGFMLVRXCIYSY-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
1
PK Parameters
3
Publications
0
Known Names
Molecular Properties
313.8
MW (Da)
4.27
ALogP
3
HBA
1
HBD
46.9
PSA (Ų)
0.78
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 5.76
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Molecular identity unknown CHEMBL612546 | EC50 | 5.76 | 5.76 | 1730.0 | 1 |
Pharmacokinetic Data
| Parameter | Value | Units | Species |
|---|---|---|---|
| T1/2 | 3.3 | hr | Homo sapiens |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Molecular identity unknown | EC50 | = | 1730.0 | nM | 5.76 | Upregulation of utrophin transcription in mouse H2K cells after 48 hrs by lucife... | 21741236 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 21741236 | 10.1016/j.bmcl.2011.06.047 | Molecular identity unknown | 2 |
| 21741236 | 10.1016/j.bmcl.2011.06.047 | No relevant target | 1 |
| 21741236 | 10.1016/j.bmcl.2011.06.047 | Liver microsomes | 1 |
Data from ChEMBL 36 via Core Engine