Compound Detail
CHEMBL182073
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Basic Information
| ChEMBL ID | CHEMBL182073 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DDWGQGZPYDSYEL-GJZGRUSLSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
354.4
MW (Da)
2.72
ALogP
6
HBA
0
HBD
63.2
PSA (Ų)
0.79
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.16
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Trypanosoma cruzi CHEMBL368 | IC50 | 6.16 | 6.16 | 700.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Trypanosoma cruzi | IC50 | = | 700.0 | nM | 6.16 | Trypanocidal activity against amastigote forms of Y strain of Trypanosoma cruzi | 15603944 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15603944 | 10.1016/j.bmcl.2004.10.079 | Trypanosoma cruzi | 5 |
Data from ChEMBL 36 via Core Engine