Assay Detail
Functional
CHEMBL833861
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Trypanocidal activity against amastigote forms of Y strain of Trypanosoma cruzi
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Trypanosoma cruzi |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Trypanocidal activity of (-)-cubebin derivatives against free amastigote forms of Trypanosoma cruzi.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.37 | 6.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL182073 | — | — | 1 | 6.16 |
| CHEMBL110 | BENZNIDAZOLE | 4.0 | 1 | 6.10 |
| CHEMBL360792 | — | — | 1 | 5.33 |
| CHEMBL365302 | — | — | 1 | 5.24 |
| CHEMBL442781 | — | — | 1 | 4.02 |
| CHEMBL360063 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL182073 | — | IC50 | = | 700.0 | nM | 6.16 |
| CHEMBL110 | BENZNIDAZOLE | IC50 | = | 800.0 | nM | 6.10 |
| CHEMBL360792 | — | IC50 | = | 4700.0 | nM | 5.33 |
| CHEMBL365302 | — | IC50 | = | 5700.0 | nM | 5.24 |
| CHEMBL442781 | — | IC50 | = | 95300.0 | nM | 4.02 |
| CHEMBL360063 | — | IC50 | ~ | 15000000.0 | nM | - |