Compound Detail
CHEMBL1908323
LEVOMETHORPHAN 🧪 Phase II
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🧪 Phase II
Basic Information
| ChEMBL ID | CHEMBL1908323 |
| Name | LEVOMETHORPHAN |
| Phase | Phase II |
| Structure Type | MOL |
| InChI Key | MKXZASYAUGDDCJ-CGTJXYLNSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
7
Known Names
Molecular Properties
271.4
MW (Da)
3.38
ALogP
2
HBA
0
HBD
12.5
PSA (Ų)
0.78
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Chirality | Single Enantiomer |
Activity Summary
Ki 1 meas. best 5.47
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate NMDA receptor CHEMBL1907608 | Ki | 5.47 | 5.47 | 3360.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate NMDA receptor | Ki | = | 3360.0 | nM | 5.47 | Displacement of [3H]MK801 from NMDA receptor in rat brain neuronal membrane | 19345586 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19345586 | 10.1016/j.bmc.2009.03.025 | Glutamate NMDA receptor | 2 |
| 2213833 | 10.1021/jm00172a021 | Opioid receptor | 1 |
Data from ChEMBL 36 via Core Engine