Compound Detail
CHEMBL1914671
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1914671 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DZDYJTGGGDWVDJ-CYBMUJFWSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
332.4
MW (Da)
4.94
ALogP
3
HBA
2
HBD
53.6
PSA (Ų)
0.56
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.48
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Epidermal growth factor receptor CHEMBL203 | IC50 | 7.48 | 7.48 | 33.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Epidermal growth factor receptor | IC50 | = | 33.0 | nM | 7.48 | Inhibition of EGFR by Z-LYTE assay | 22018877 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 22018877 | 10.1016/j.ejmech.2011.10.012 | Epidermal growth factor receptor | 2 |
Data from ChEMBL 36 via Core Engine