Compound Detail
CHEMBL191480
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Basic Information
| ChEMBL ID | CHEMBL191480 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZLQITWMSLIPBGT-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
517.5
MW (Da)
6.32
ALogP
6
HBA
1
HBD
63.3
PSA (Ų)
0.33
QED
2
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 8.15
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Coagulation factor X CHEMBL244 | Ki | 8.15 | 8.15 | 7.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Coagulation factor X | Ki | = | 7.0 | nM | 8.15 | Binding affinity for human factor Xa | 15999990 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15999990 | 10.1021/jm0490540 | Coagulation factor X | 1 |
Data from ChEMBL 36 via Core Engine