Compound Detail
CHEMBL191581
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Basic Information
| ChEMBL ID | CHEMBL191581 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QOEAHTBZGUOMCB-GHRIWEEISA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
361.4
MW (Da)
3.26
ALogP
7
HBA
3
HBD
102.3
PSA (Ų)
0.60
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.1
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Mitogen-activated protein kinase 10 CHEMBL4092 | IC50 | 7.1 | 7.1 | 80.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Mitogen-activated protein kinase 10 | IC50 | = | 80.0 | nM | 7.1 | Inhibition of rat c-Jun N-terminal kinase 3 | 15999997 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15999997 | 10.1021/jm0310986 | Mitogen-activated protein kinase 10 | 1 |
| 15999997 | 10.1021/jm0310986 | Jurkat | 1 |
Data from ChEMBL 36 via Core Engine