Mitogen-activated protein kinase 10 · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt P49187. Use UniProt P49187 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P49187 as the stable identity anchor, then attach disease evidence before program review.
Mitogen-activated protein kinase 10
Review this target as Mitogen-activated protein kinase 10, mapped to UniProt P49187. Sequence length is 464 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Mitogen-activated protein kinase 10 as ChEMBL target CHEMBL4092, mapped to UniProt P49187. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Mitogen-activated protein kinase 10 |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P49187 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Mitogen-activated protein kinase 10 |
| UniProt Accession | P49187 |
| Component Type | Protein |
| Sequence Length | 464 aa |
Mitogen-activated protein kinase 10
Review this target as Mitogen-activated protein kinase 10, mapped to UniProt P49187. Sequence length is 464 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3220495 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL363355 | 7.39 | IC50 | 41.0 | Preclinical |
| CHEMBL585951 | 7.27 | IC50 | 54.0 | Preclinical |
| CHEMBL363254 | 7.19 | IC50 | 65.0 | Preclinical |
| CHEMBL191581 | 7.1 | IC50 | 80.0 | Preclinical |
| CHEMBL372708 | 7.1 | IC50 | 80.0 | Preclinical |
| CHEMBL1788116 | 6.92 | IC50 | 120.0 | Preclinical |
| CHEMBL371113 | 6.84 | IC50 | 143.0 | Preclinical |
| CHEMBL189841 | 6.83 | IC50 | 147.0 | Preclinical |
| CHEMBL571626 | 6.68 | IC50 | 210.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 11 | 10 | 6.3 |
| single protein format | 4 | 45 | 6.1 |
| tissue-based format | 1 | 0 | — |