Compound Detail
CHEMBL191780
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Basic Information
| ChEMBL ID | CHEMBL191780 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZGOSZSGVOJASTJ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
410.0
MW (Da)
6.69
ALogP
3
HBA
0
HBD
21.1
PSA (Ų)
0.43
QED
1
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.72
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Corticotropin-releasing factor receptor 1 CHEMBL1800 | Ki | 5.72 | 5.72 | 1900.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Corticotropin-releasing factor receptor 1 | Ki | = | 1900.0 | nM | 5.72 | Inhibition of [125I]sauvagine binding to corticotropin releasing factor receptor... | 15943483 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15943483 | 10.1021/jm050070m | Corticotropin-releasing factor receptor 1 | 1 |
Data from ChEMBL 36 via Core Engine