Compound Detail
CHEMBL192335
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL192335 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CNNDCWIMMAGCAK-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
378.9
MW (Da)
5.41
ALogP
4
HBA
0
HBD
44.9
PSA (Ų)
0.61
QED
1
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 7.21
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Corticotropin-releasing factor receptor 1 CHEMBL1800 | Ki | 7.21 | 7.21 | 62.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Corticotropin-releasing factor receptor 1 | Ki | = | 62.0 | nM | 7.21 | Inhibition of [125I]sauvagine binding to corticotropin releasing factor receptor... | 15943483 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15943483 | 10.1021/jm050070m | Corticotropin-releasing factor receptor 1 | 1 |
Data from ChEMBL 36 via Core Engine