Compound Detail
CHEMBL1966883
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1966883 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JNKVMKJVDXSLEG-YPKPFQOOSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
420.1
MW (Da)
4.18
ALogP
3
HBA
2
HBD
58.2
PSA (Ų)
0.63
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 4.67
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| HT-22 CHEMBL614316 | EC50 | 4.67 | 4.67 | 21300.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| HT-22 | EC50 | = | 21300.0 | nM | 4.67 | Cytoprotective activity against tunicamycin-induced cell death in mouse HT22 cel... | 29122482 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 29122482 | 10.1016/j.bmcl.2017.10.069 | HT-22 | 7 |
| 28743492 | 10.1016/j.bmc.2017.07.009 | HepG2 | 1 |
Data from ChEMBL 36 via Core Engine