Compound Detail
CHEMBL199753
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Basic Information
| ChEMBL ID | CHEMBL199753 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BGNFQBMDFVWHBS-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
299.3
MW (Da)
3.86
ALogP
3
HBA
1
HBD
58.6
PSA (Ų)
0.58
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.39
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Methionine aminopeptidase CHEMBL3423 | IC50 | 6.39 | 6.39 | 403.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Methionine aminopeptidase | IC50 | = | 403.0 | nM | 6.39 | Inhibition of Co2+ loaded MetAP expressed in Escherichia coli | 16420038 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 16420038 | 10.1021/jm050476z | Methionine aminopeptidase | 2 |
Data from ChEMBL 36 via Core Engine