Compound Detail
CHEMBL2059274
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Basic Information
| ChEMBL ID | CHEMBL2059274 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WYIZNABLHZTYJV-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
1
Known Names
Molecular Properties
293.3
MW (Da)
2.60
ALogP
4
HBA
2
HBD
83.5
PSA (Ų)
0.85
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.38
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| M-phase inducer phosphatase 2 CHEMBL4804 | IC50 | 5.38 | 5.38 | 4200.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| M-phase inducer phosphatase 2 | IC50 | = | 4200.0 | nM | 5.38 | Inhibition of recombinant phosphatase activity of Cdc25B catalytic domain expres... | 22524450 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 22524450 | 10.1021/jm201624h | M-phase inducer phosphatase 2 | 3 |
Data from ChEMBL 36 via Core Engine