Compound Detail
CHEMBL2068576
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Basic Information
| ChEMBL ID | CHEMBL2068576 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PKVFAQQODZPIMO-NSHDSACASA-N |
1
Targets
4
Activities
2
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
283.1
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 6.78
Ki 2 meas. best 5.41
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Beta-2 adrenergic receptor CHEMBL210 | EC50 | 6.78 | 6.78 | 166.0 | 2 |
| Beta-2 adrenergic receptor CHEMBL210 | Ki | 5.41 | 5.41 | 3890.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Beta-2 adrenergic receptor | EC50 | = | 166.0 | nM | 6.78 | Agonist activity at recombinant human beta2 adrenoceptor expressed in HEK293T ce... | 22182578 |
| Beta-2 adrenergic receptor | EC50 | = | 165.96 | nM | 6.78 | Agonist activity at recombinant human beta2 adrenoceptor expressed in HEK293T ce... | 22182578 |
| Beta-2 adrenergic receptor | Ki | = | 3890.0 | nM | 5.41 | Displacement of [3H]-DHA from recombinant human beta2 adrenoceptor expressed in ... | 22182578 |
| Beta-2 adrenergic receptor | Ki | = | 3890.45 | nM | 5.41 | Displacement of [3H]-DHA from recombinant human beta2 adrenoceptor expressed in ... | 22182578 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 22182578 | 10.1016/j.bmc.2011.11.054 | Beta-2 adrenergic receptor | 7 |
Data from ChEMBL 36 via Core Engine