Compound Detail
CHEMBL206880
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL206880 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JBKLGOKYTCIIQM-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
349.4
MW (Da)
4.55
ALogP
4
HBA
2
HBD
67.8
PSA (Ų)
0.62
QED
0
Ro5 Violations
8
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 5.69
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Free fatty acid receptor 1 CHEMBL4422 | EC50 | 5.69 | 5.69 | 2041.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Free fatty acid receptor 1 | EC50 | = | 2041.74 | nM | 5.69 | Agonist potency at human GPR40 expressed in CHO cells | 16439116 |
| Free fatty acid receptor 1 | EC50 | = | 2041.0 | nM | 5.69 | Agonist activity at FFA1 receptor (unknown origin) stably expressed in CHO cells... | 31279294 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 16439116 | 10.1016/j.bmcl.2006.01.007 | Free fatty acid receptor 1 | 2 |
| 31279294 | 10.1016/j.ejmech.2019.06.087 | Free fatty acid receptor 1 | 1 |
Data from ChEMBL 36 via Core Engine