Compound Detail
CHEMBL2071425
DIACETYLGERANYLPHENAZINEDIOL Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL2071425 |
| Name | DIACETYLGERANYLPHENAZINEDIOL |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PCGWNGWRZPYWHR-SFQUDFHCSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names
Molecular Properties
432.5
MW (Da)
5.87
ALogP
6
HBA
0
HBD
78.4
PSA (Ų)
0.20
QED
1
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.7
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Acetylcholinesterase CHEMBL220 | IC50 | 5.7 | 5.7 | 2010.0 | 1 |
| Bacillus subtilis CHEMBL359 | IC50 | 4.89 | 4.89 | 13000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Acetylcholinesterase | IC50 | = | 2010.0 | nM | 5.7 | Inhibition of human AChE pre-incubated for 10 mins before acetylthiocholine iodi... | 22775474 |
| Bacillus subtilis | IC50 | = | 13000.0 | nM | 4.89 | Antimicrobial activity against Bacillus subtilis DSM 347 incubated for 5 hrs by ... | 22775474 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 22775474 | 10.1021/np2009626 | Acetylcholinesterase | 1 |
| 22775474 | 10.1021/np2009626 | Bacillus subtilis | 1 |
| 22775474 | 10.1021/np2009626 | ADMET | 1 |
| 22775474 | 10.1021/np2009626 | Candida albicans | 1 |
| 22775474 | 10.1021/np2009626 | Xanthomonas campestris | 1 |
Data from ChEMBL 36 via Core Engine