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Compound Detail

CHEMBL2110892

BIETAMIVERINE
🧪 Phase II
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🧪 Phase II
CCN(CC)CCOC(=O)C(c1ccccc1)N1CCCCC1

Basic Information

ChEMBL ID CHEMBL2110892
Name BIETAMIVERINE
Phase Phase II
Structure Type MOL
InChI Key JGTJANXYSNVLMQ-UHFFFAOYSA-N

Known Names

Bietamiverina Bietamiverine
4
Targets
6
Activities
1
Assay Types
0
PK Parameters
7
Publications
2
Known Names

Molecular Properties

318.5
MW (Da)
3.10
ALogP
4
HBA
0
HBD
32.8
PSA (Ų)
0.69
QED
0
Ro5 Violations
8
Rot. Bonds

Drug Information

Molecule Type Small molecule
Chirality Racemic
USAN Stem -verine

Extended Properties

Molecular Formula C19H30N2O2
MW 318.46
Aromatic Rings 1
Heavy Atoms 23
NP-Likeness -1.21

Activity Summary

Ki 6 meas. best 6.73

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Muscarinic acetylcholine receptor M3
CHEMBL245
Ki 6.73 6.73 186.0 1
Muscarinic acetylcholine receptor M1
CHEMBL216
Ki 6.57 6.43 271.0 2
Unchecked
CHEMBL612545
Ki 6.29 6.29 517.0 2
Muscarinic acetylcholine receptor M2
CHEMBL211
Ki 5.99 5.99 1020.0 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
23523385 10.1016/j.bmc.2013.01.072 Muscarinic acetylcholine receptor M1 and M3 2
23523385 10.1016/j.bmc.2013.01.072 Muscarinic acetylcholine receptor M1 2
23523385 10.1016/j.bmc.2013.01.072 Unchecked 2
- 10.6019/CHEMBL4651402 SARS-CoV-2 2
23523385 10.1016/j.bmc.2013.01.072 Muscarinic acetylcholine receptors; M1 & M2 1
23523385 10.1016/j.bmc.2013.01.072 Muscarinic acetylcholine receptor M3 1
23523385 10.1016/j.bmc.2013.01.072 Muscarinic acetylcholine receptor M2 1

Data from ChEMBL 36 via Core Engine