Compound Detail
CHEMBL211630
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Basic Information
| ChEMBL ID | CHEMBL211630 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FPRZKGJHBUTBSJ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
393.9
MW (Da)
4.62
ALogP
3
HBA
2
HBD
82.0
PSA (Ų)
0.73
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.8
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Human immunodeficiency virus 1 CHEMBL378 | EC50 | 6.8 | 6.8 | 160.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Human immunodeficiency virus 1 | EC50 | = | 160.0 | nM | 6.8 | Antiviral activity against HIV1 | 16782337 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 16782337 | 10.1016/j.bmcl.2006.05.073 | HEK293 | 1 |
| 16782337 | 10.1016/j.bmcl.2006.05.073 | Human immunodeficiency virus 1 | 1 |
Data from ChEMBL 36 via Core Engine