Compound Detail
CHEMBL2151043
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Basic Information
| ChEMBL ID | CHEMBL2151043 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FLORGHJNTGTZHV-AEFFLSMTSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
329.4
MW (Da)
3.37
ALogP
3
HBA
0
HBD
46.6
PSA (Ų)
0.29
QED
0
Ro5 Violations
10
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 4.08
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Fatty-acid amide hydrolase 1 CHEMBL2243 | IC50 | 4.08 | 4.08 | 82800.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Fatty-acid amide hydrolase 1 | IC50 | = | 82800.0 | nM | 4.08 | Reversible inhibition of human recombinant FAAH assessed as hydrolysis of [3H]-A... | 21899370 |
| Fatty-acid amide hydrolase 1 | IC50 | = | 83176.38 | nM | 4.08 | Reversible inhibition of human recombinant FAAH assessed as hydrolysis of [3H]-A... | 21899370 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 21899370 | 10.1021/jm200723m | Fatty-acid amide hydrolase 1 | 2 |
Data from ChEMBL 36 via Core Engine