Compound Detail
CHEMBL215110
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Basic Information
| ChEMBL ID | CHEMBL215110 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | XZIYBTNLDSSPBD-SRQNXYAJSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
494.3
MW (Da)
4.46
ALogP
6
HBA
3
HBD
96.2
PSA (Ų)
0.23
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 8.03
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Amyloid-beta precursor protein CHEMBL2487 | Ki | 8.03 | 8.03 | 9.4 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Amyloid-beta precursor protein | Ki | = | 9.37 | nM | 8.03 | Displacement of [125I]IMSB from beta amyloid protein 40 | 17004725 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17004725 | 10.1021/jm0607193 | Amyloid-beta precursor protein | 1 |
Data from ChEMBL 36 via Core Engine