Compound Detail
CHEMBL2151433
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Basic Information
| ChEMBL ID | CHEMBL2151433 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZBTVTNFEAMZJOY-MJGOQNOKSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
315.5
MW (Da)
3.84
ALogP
2
HBA
0
HBD
29.5
PSA (Ų)
0.35
QED
0
Ro5 Violations
11
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 4.05
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Fatty-acid amide hydrolase 1 CHEMBL2243 | IC50 | 4.05 | 4.05 | 88600.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Fatty-acid amide hydrolase 1 | IC50 | = | 88600.0 | nM | 4.05 | Reversible inhibition of human recombinant FAAH assessed as hydrolysis of [3H]-A... | 21899370 |
| Fatty-acid amide hydrolase 1 | IC50 | = | 89125.09 | nM | 4.05 | Reversible inhibition of human recombinant FAAH assessed as hydrolysis of [3H]-A... | 21899370 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 21899370 | 10.1021/jm200723m | Fatty-acid amide hydrolase 1 | 2 |
Data from ChEMBL 36 via Core Engine