Compound Detail
CHEMBL2152500
EMPETRIFRANZINAN C Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL2152500 |
| Name | EMPETRIFRANZINAN C |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FUOLYAMVOGPERE-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
8
Publications
0
Known Names
Molecular Properties
344.4
MW (Da)
4.83
ALogP
4
HBA
1
HBD
55.8
PSA (Ų)
0.80
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.04
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| NON-PROTEIN TARGET CHEMBL3879801 | IC50 | 5.04 | 5.04 | 9200.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| NON-PROTEIN TARGET | IC50 | = | 9200.0 | nM | 5.04 | Antiangiogenic activity in SV-40T transfected human HMEC1 cells assessed as inhi... | 23030826 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 26358281 | 10.1016/j.bmc.2015.08.028 | PC-3 | 2 |
| 26358281 | 10.1016/j.bmc.2015.08.028 | HT-29 | 2 |
| 23030826 | 10.1021/np300237n | NON-PROTEIN TARGET | 1 |
| 26358281 | 10.1016/j.bmc.2015.08.028 | Human immunodeficiency virus 1 | 1 |
| 26358281 | 10.1016/j.bmc.2015.08.028 | MT4 | 1 |
| 26358281 | 10.1016/j.bmc.2015.08.028 | Escherichia coli | 1 |
| 26358281 | 10.1016/j.bmc.2015.08.028 | Staphylococcus aureus | 1 |
| 26358281 | 10.1016/j.bmc.2015.08.028 | Enterococcus faecalis | 1 |
Data from ChEMBL 36 via Core Engine