Compound Detail
CHEMBL215363
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Basic Information
| ChEMBL ID | CHEMBL215363 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PJVQVFHLQKKXOY-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
391.8
MW (Da)
4.86
ALogP
4
HBA
2
HBD
76.2
PSA (Ų)
0.52
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 5.14
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Photoreceptor-specific nuclear receptor CHEMBL4374 | EC50 | 5.14 | 5.14 | 7200.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Photoreceptor-specific nuclear receptor | EC50 | = | 7200.0 | nM | 5.14 | Agonist activity at NR2E3 by luciferase NCOR release assay in CHO cells | 16879962 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 16879962 | 10.1016/j.bmcl.2006.07.056 | Photoreceptor-specific nuclear receptor | 2 |
Data from ChEMBL 36 via Core Engine