Compound Detail
CHEMBL217894
DECYLUBIQUINONE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL217894 |
| Name | DECYLUBIQUINONE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VMEGFMNVSYVVOM-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
13
Publications
0
Known Names
Molecular Properties
322.4
MW (Da)
4.49
ALogP
4
HBA
0
HBD
52.6
PSA (Ų)
0.42
QED
0
Ro5 Violations
11
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 7.25
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| NON-PROTEIN TARGET CHEMBL3879801 | EC50 | 7.25 | 7.25 | 56.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| NON-PROTEIN TARGET | EC50 | = | 56.0 | nM | 7.25 | Cytoprotective activity against BSO-induced cell death in human Friedreich's ata... | 24900738 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 23313093 | 10.1016/j.bmc.2012.11.051 | Unchecked | 15 |
| 24900738 | 10.1021/ml400130z | Unchecked | 11 |
| 23473946 | 10.1016/j.bmc.2013.01.075 | CCRF-CEM | 8 |
| 23473946 | 10.1016/j.bmc.2013.01.075 | Unchecked | 8 |
| 17228860 | 10.1021/jm060687j | Dihydroorotate dehydrogenase (quinone), mitochondrial | 4 |
| 18461966 | 10.1021/jf800331r | Coptotermes formosanus | 4 |
| 23313093 | 10.1016/j.bmc.2012.11.051 | CCRF-CEM | 4 |
| 23313093 | 10.1016/j.bmc.2012.11.051 | GM15850 | 4 |
| 23313093 | 10.1016/j.bmc.2012.11.051 | NON-PROTEIN TARGET | 2 |
| 17228860 | 10.1021/jm060687j | Dihydroorotate dehydrogenase | 1 |
| 23062825 | 10.1016/j.bmc.2012.09.040 | Acetylcholinesterase | 1 |
| 23062825 | 10.1016/j.bmc.2012.09.040 | Cholinesterase | 1 |
| 24900738 | 10.1021/ml400130z | NON-PROTEIN TARGET | 1 |
Data from ChEMBL 36 via Core Engine