Compound Detail
CHEMBL2179495
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Basic Information
| ChEMBL ID | CHEMBL2179495 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | TYOUBEAPKZQVRT-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
345.5
MW (Da)
2.67
ALogP
4
HBA
0
HBD
66.1
PSA (Ų)
0.84
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.3
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Scavenger receptor class B member 1 CHEMBL1914272 | IC50 | 7.3 | 7.3 | 50.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Scavenger receptor class B member 1 | IC50 | = | 50.0 | nM | 7.3 | Inhibition of human SRB1-mediated Hepatitis C virus genotype 2a entry into human... | 22784640 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 22784640 | 10.1016/j.bmcl.2012.06.038 | Scavenger receptor class B member 1 | 1 |
Data from ChEMBL 36 via Core Engine