Compound Detail
CHEMBL2235358
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Basic Information
| ChEMBL ID | CHEMBL2235358 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZMTCLMVXXDGKGK-KAVGSWPWSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
6
Publications
0
Known Names
Molecular Properties
352.4
MW (Da)
3.94
ALogP
5
HBA
2
HBD
76.0
PSA (Ų)
0.82
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.3
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Molecular identity unknown CHEMBL612546 | EC50 | 6.3 | 6.3 | 500.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Molecular identity unknown | EC50 | = | 500.0 | nM | 6.3 | Inhibition of Wnt3A/beta-catenin signaling in HEK293 cells after 24 hrs by firef... | 24275249 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 24275249 | 10.1016/j.ejmech.2013.10.073 | Molecular identity unknown | 10 |
| - | 10.1007/s00044-011-9793-z | Escherichia coli | 9 |
| - | 10.1007/s00044-011-9793-z | Vero | 1 |
| - | 10.1007/s00044-011-9793-z | Buffalopox virus | 1 |
| - | 10.1007/s00044-011-9793-z | Camelpox virus | 1 |
| 24275249 | 10.1016/j.ejmech.2013.10.073 | U2OS | 1 |
Data from ChEMBL 36 via Core Engine