Compound Detail
CHEMBL2261914
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Basic Information
| ChEMBL ID | CHEMBL2261914 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | POPCGDXTXGSDLQ-VMPITWQZSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
214.2
MW (Da)
2.88
ALogP
3
HBA
1
HBD
50.4
PSA (Ų)
0.63
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 4.6
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| RAW264.7 CHEMBL612557 | IC50 | 4.6 | 4.6 | 24890.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| RAW264.7 | IC50 | = | 24890.0 | nM | 4.6 | Anti-inflammatory activity in Mus musculus (mouse) RAW264.7 cells assessed as in... | - |
| RAW264.7 | IC50 | = | 25118.86 | nM | 4.6 | Anti-inflammatory activity in Mus musculus (mouse) RAW264.7 cells assessed as in... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1007/s00044-011-9706-1 | RAW264.7 | 2 |
Data from ChEMBL 36 via Core Engine