Compound Detail
CHEMBL2272997
(R)-METHYL-IMIDACLOPRID Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL2272997 |
| Name | (R)-METHYL-IMIDACLOPRID |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PCQCQCIFVHSSNM-SSDOTTSWSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
9
Publications
0
Known Names
Molecular Properties
269.7
MW (Da)
1.25
ALogP
3
HBA
1
HBD
83.7
PSA (Ų)
0.51
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.02
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Nicotinic acetylcholine receptor alpha 5 subunit CHEMBL2366408 | IC50 | 6.02 | 6.02 | 950.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Nicotinic acetylcholine receptor alpha 5 subunit | IC50 | = | 950.0 | nM | 6.02 | Displacement of [3HIMI from nicotinic acetylcholine receptor in Musca domestica ... | 12834274 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1584/jpestics.29.43 | Periplaneta americana | 3 |
| 12834274 | 10.1271/bbb.67.980 | Musca domestica | 2 |
| - | 10.1584/jpestics.29.43 | Myzus persicae | 2 |
| - | 10.1584/jpestics.29.43 | Nephotettix cincticeps | 2 |
| - | 10.1584/jpestics.29.43 | Aulacophora | 2 |
| - | 10.1584/jpestics.29.43 | Musca domestica | 2 |
| 12834274 | 10.1271/bbb.67.980 | Nicotinic acetylcholine receptor alpha 5 subunit | 1 |
| 12834274 | 10.1271/bbb.67.980 | Periplaneta americana | 1 |
| - | 10.1584/jpestics.29.43 | Nicotinic acetylcholine receptor alpha 5 subunit | 1 |
Data from ChEMBL 36 via Core Engine