Nicotinic acetylcholine receptor alpha 5 subunit · SINGLE PROTEIN · Musca domestica
This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.
Move to another high-traffic target or paste a specific ChEMBL target ID.
Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-13Protein identity stays anchored to UniProt A9XFY4. Use UniProt A9XFY4 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt A9XFY4 as the stable identity anchor, then attach disease evidence before program review.
Neuronal acetylcholine receptor subunit alpha-7-like precursor
Review this target as Nicotinic acetylcholine receptor alpha 5 subunit, mapped to UniProt A9XFY4. ChEMBL maps the protein component as Neuronal acetylcholine receptor subunit alpha-7-like precursor. Sequence length is 781 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Nicotinic acetylcholine receptor alpha 5 subunit as ChEMBL target CHEMBL2366408, mapped to UniProt A9XFY4. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether Nicotinic acetylcholine receptor alpha 5 subunit is the right protein anchor across sources, using UniProt A9XFY4 as the stable mapping.
Jump to Protein ContextUse this block first when you need the strongest disease program and evidence level in one place.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardVerify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | Nicotinic acetylcholine receptor alpha 5 subunit |
| Target Type | SINGLE PROTEIN |
| Organism | Musca domestica |
| UniProt | A9XFY4 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Neuronal acetylcholine receptor subunit alpha-7-like precursor |
| UniProt Accession | A9XFY4 |
| Component Type | Protein |
| Sequence Length | 781 aa |
Neuronal acetylcholine receptor subunit alpha-7-like precursor
Review this target as Nicotinic acetylcholine receptor alpha 5 subunit, mapped to UniProt A9XFY4. ChEMBL maps the protein component as Neuronal acetylcholine receptor subunit alpha-7-like precursor. Sequence length is 781 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL259727 | 8.74 | IC50 | 1.8 | Preclinical |
| CHEMBL406819 | 8.59 | IC50 | 2.6 | Preclinical |
| CHEMBL2272685 | 8.4 | Ki | 4.0 | Preclinical |
| CHEMBL406819 | 8.34 | Ki | 4.6 | Preclinical |
| CHEMBL2272690 | 8.22 | Ki | 6.0 | Preclinical |
| CHEMBL148390 | 8.15 | IC50 | 7.1 | Preclinical |
| CHEMBL2251730 | 7.92 | IC50 | 12.0 | Preclinical |
| CHEMBL2269823 | 7.85 | IC50 | 14.0 | Preclinical |
| CHEMBL2269822 | 7.8 | IC50 | 16.0 | Preclinical |
| CHEMBL2251976 | 7.77 | Ki | 17.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 11 | 76 | 6.1 |