Compound Detail
CHEMBL228669
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL228669 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WEIOHZVVRWVQDS-UHFFFAOYSA-N |
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
359.5
MW (Da)
2.23
ALogP
6
HBA
1
HBD
58.0
PSA (Ų)
0.77
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 5.15
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Plasma CHEMBL613652 | IC50 | 5.15 | 5.0167 | 7100.0 | 3 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Plasma | IC50 | = | 7100.0 | nM | 5.15 | Inhibition of 5.0 ug/mL collagen-induced platelet aggregation in human platelet ... | 17500510 |
| Plasma | IC50 | = | 10700.0 | nM | 4.97 | Inhibition of A23187-induced platelet aggregation in human platelet rich plasma | 17500510 |
| Plasma | IC50 | = | 11800.0 | nM | 4.93 | Inhibition of ADP-induced platelet aggregation in human platelet rich plasma | 17500510 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17500510 | 10.1021/jm0611511 | Plasma | 3 |
Data from ChEMBL 36 via Core Engine