Compound Detail
CHEMBL2322681
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Basic Information
| ChEMBL ID | CHEMBL2322681 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LREADVAQGARKQU-SHTZXODSSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
322.4
MW (Da)
3.65
ALogP
4
HBA
3
HBD
73.8
PSA (Ų)
0.69
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 7.57
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cell division cycle 7-related protein kinase CHEMBL5443 | Ki | 7.57 | 7.57 | 27.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cell division cycle 7-related protein kinase | Ki | = | 27.0 | nM | 7.57 | Inhibition of human Cdc7 using biotin-C6linker-TPSDSLIYDDGLS as substrate after ... | 24900653 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 24900653 | 10.1021/ml300348c | Cell division cycle 7-related protein kinase | 1 |
Data from ChEMBL 36 via Core Engine