Compound Detail
CHEMBL2323892
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Basic Information
| ChEMBL ID | CHEMBL2323892 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZFDYJSAPGBAVRK-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
352.2
MW (Da)
5.63
ALogP
2
HBA
2
HBD
53.1
PSA (Ų)
0.64
QED
1
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.16
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Uracil-DNA glycosylase CHEMBL3988595 | IC50 | 5.16 | 5.16 | 7000.0 | 1 |
| Vaccinia virus CHEMBL613493 | IC50 | 5.16 | 5.16 | 7000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Vaccinia virus | IC50 | = | 7000.0 | nM | 5.16 | Antiviral activity against Vaccinia virus WR infected in African green monkey BS... | 23527789 |
| Uracil-DNA glycosylase | IC50 | = | 7000.0 | nM | 5.16 | Viral Plaque Reduction Assay: African green monkey kidney BSC-1 cells were grown... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 23527789 | 10.1021/jm301735k | Unchecked | 1 |
| 23527789 | 10.1021/jm301735k | BSC-1 | 1 |
| 23527789 | 10.1021/jm301735k | Vaccinia virus | 1 |
Data from ChEMBL 36 via Core Engine