Uracil-DNA glycosylase · SINGLE PROTEIN · Vaccinia virus (strain Copenhagen) (VACV)
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As of 2026-09-14Protein identity stays anchored to UniProt P20536. Use UniProt P20536 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P20536 as the stable identity anchor, then attach disease evidence before program review.
Uracil-DNA glycosylase
Review this target as Uracil-DNA glycosylase, mapped to UniProt P20536. Sequence length is 218 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Uracil-DNA glycosylase as ChEMBL target CHEMBL3988595, mapped to UniProt P20536. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Uracil-DNA glycosylase |
| Target Type | SINGLE PROTEIN |
| Organism | Vaccinia virus (strain Copenhagen) (VACV) |
| UniProt | P20536 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Uracil-DNA glycosylase |
| UniProt Accession | P20536 |
| Component Type | Protein |
| Sequence Length | 218 aa |
Uracil-DNA glycosylase
Review this target as Uracil-DNA glycosylase, mapped to UniProt P20536. Sequence length is 218 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2323903 | 7.38 | IC50 | 42.0 | Preclinical |
| CHEMBL3894087 | 7.34 | IC50 | 46.0 | Preclinical |
| CHEMBL2327013 | 6.68 | IC50 | 208.0 | Preclinical |
| CHEMBL2323902 | 6.61 | IC50 | 244.0 | Preclinical |
| CHEMBL2323892 | 5.16 | IC50 | 7000.0 | Preclinical |
| CHEMBL2323893 | 5.05 | IC50 | 9000.0 | Preclinical |
| CHEMBL2323897 | 5.0 | IC50 | 10000.0 | Preclinical |
| CHEMBL2323900 | 4.75 | IC50 | 18000.0 | Preclinical |
| CHEMBL2327027 | 4.72 | IC50 | 19000.0 | Preclinical |
| CHEMBL2323899 | 4.68 | IC50 | 21000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 34 | 4.8 |