Compound Detail
CHEMBL2324295
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Basic Information
| ChEMBL ID | CHEMBL2324295 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IWQYRZCSIXTGCN-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
321.7
MW (Da)
3.41
ALogP
5
HBA
1
HBD
115.4
PSA (Ų)
0.68
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 5.75
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Trypanosoma brucei brucei CHEMBL612851 | EC50 | 5.75 | 5.75 | 1800.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Trypanosoma brucei brucei | EC50 | = | 1800.0 | nM | 5.75 | Antitrypanosomal activity against blood stream stage of Trypanosoma brucei bruce... | 23484493 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 23484493 | 10.1021/jm301687p | Trypanosoma brucei brucei | 1 |
| 33854703 | 10.1021/acsmedchemlett.1c00029 | Nuclear receptor ROR-gamma | 1 |
| 33854703 | 10.1021/acsmedchemlett.1c00029 | Peroxisome proliferator-activated receptor gamma | 1 |
Data from ChEMBL 36 via Core Engine