Compound Detail
CHEMBL2325785
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Basic Information
| ChEMBL ID | CHEMBL2325785 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UNJMPTSTBHSHCU-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
392.8
MW (Da)
5.04
ALogP
4
HBA
2
HBD
100.9
PSA (Ų)
0.37
QED
1
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 5.39
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Trypanosoma brucei brucei CHEMBL612851 | EC50 | 5.39 | 5.39 | 4100.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Trypanosoma brucei brucei | EC50 | = | 4100.0 | nM | 5.39 | Antitrypanosomal activity against blood stream stage of Trypanosoma brucei bruce... | 23484493 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 23484493 | 10.1021/jm301687p | Trypanosoma brucei brucei | 1 |
Data from ChEMBL 36 via Core Engine