Compound Detail
CHEMBL2326893
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Basic Information
| ChEMBL ID | CHEMBL2326893 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NMCYSPSPYOBVHL-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
491.4
MW (Da)
5.92
ALogP
4
HBA
1
HBD
37.4
PSA (Ų)
0.30
QED
1
Ro5 Violations
9
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 6.45
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Amyloid-beta precursor protein CHEMBL2487 | Ki | 6.45 | 6.45 | 353.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Amyloid-beta precursor protein | Ki | = | 353.0 | nM | 6.45 | Displacement of [125I]IMPY from amyloid beta (1 to 42) (unknown origin) after 3 ... | 23344363 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 23344363 | 10.1016/j.ejmech.2012.12.020 | Unchecked | 2 |
| 23344363 | 10.1016/j.ejmech.2012.12.020 | Amyloid-beta precursor protein | 1 |
Data from ChEMBL 36 via Core Engine