Compound Detail
CHEMBL2333043
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL2333043 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HXOGFPFEQNRKFH-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
264.3
MW (Da)
0.55
ALogP
5
HBA
2
HBD
107.8
PSA (Ų)
0.76
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.6
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Fatty-acid amide hydrolase 1 CHEMBL3229 | IC50 | 7.6 | 7.6 | 25.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Fatty-acid amide hydrolase 1 | IC50 | = | 25.0 | nM | 7.6 | Inhibition of rat FAAH using [3H]-AEA as substrate by liquid chromatography-mass... | 31945644 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 23614460 | 10.1021/jm301879g | No relevant target | 1 |
| 23614460 | 10.1021/jm301879g | Acid ceramidase | 1 |
| 31945644 | 10.1016/j.ejmech.2019.111953 | Fatty-acid amide hydrolase 1 | 1 |
Data from ChEMBL 36 via Core Engine