Assay Detail
Binding
CHEMBL4683843
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of rat FAAH using [3H]-AEA as substrate by liquid chromatography-mass spectrometry
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
A perspective review on fatty acid amide hydrolase (FAAH) inhibitors as potential therapeutic agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 8.04 | 9.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4749527 | — | — | 1 | 9.52 |
| CHEMBL4752215 | — | — | 1 | 9.10 |
| CHEMBL4784097 | — | — | 1 | 8.52 |
| CHEMBL460499 | CARMOFUR | 2.0 | 1 | 7.60 |
| CHEMBL2333043 | — | — | 1 | 7.60 |
| CHEMBL4754566 | — | — | 1 | 7.60 |
| CHEMBL2333065 | — | — | 1 | 6.31 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4749527 | — | IC50 | = | 0.3 | nM | 9.52 |
| CHEMBL4752215 | — | IC50 | = | 0.8 | nM | 9.10 |
| CHEMBL4784097 | — | IC50 | = | 3.0 | nM | 8.52 |
| CHEMBL460499 | CARMOFUR | IC50 | = | 25.0 | nM | 7.60 |
| CHEMBL2333043 | — | IC50 | = | 25.0 | nM | 7.60 |
| CHEMBL4754566 | — | IC50 | = | 25.0 | nM | 7.60 |
| CHEMBL2333065 | — | IC50 | = | 492.0 | nM | 6.31 |