Compound Detail
CHEMBL4754566
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Basic Information
| ChEMBL ID | CHEMBL4754566 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VQLOTZYIDCPZLI-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
297.3
MW (Da)
0.60
ALogP
6
HBA
2
HBD
110.3
PSA (Ų)
0.59
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.6
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Fatty-acid amide hydrolase 1 CHEMBL3229 | IC50 | 7.6 | 7.6 | 25.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Fatty-acid amide hydrolase 1 | IC50 | = | 25.0 | nM | 7.6 | Inhibition of rat FAAH using [3H]-AEA as substrate by liquid chromatography-mass... | 31945644 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 31945644 | 10.1016/j.ejmech.2019.111953 | Fatty-acid amide hydrolase 1 | 1 |
Data from ChEMBL 36 via Core Engine