Compound Detail
CHEMBL2336050
XANOMELINE TARTRATE 💊 Approved Drug
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💊 Approved Drug
Basic Information
| ChEMBL ID | CHEMBL2336050 |
| Name | XANOMELINE TARTRATE |
| Phase | Approved |
| Structure Type | MOL |
| InChI Key | SJSVWTMVMBGIHQ-UHFFFAOYSA-N |
| Parent Compound | CHEMBL21536 |
| Active Moiety | CHEMBL21536 |
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
8
Publications
6
Known Names
1
Indications
2
Mechanisms
Molecular Properties
281.4
MW (Da)
3.22
ALogP
5
HBA
0
HBD
38.2
PSA (Ų)
0.72
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| First Approval | 2024 |
| Availability | Prescription |
| Chirality | Achiral |
Mechanism of Action
| Mechanism | Action Type | Target | Direct | Efficacy |
|---|---|---|---|---|
| Muscarinic acetylcholine receptor M4 agonist | AGONIST | Muscarinic acetylcholine receptor M4 | ✓ | ✓ |
| Muscarinic acetylcholine receptor M1 agonist | AGONIST | Muscarinic acetylcholine receptor M1 | ✓ | ✓ |
Indications
Schizophrenia
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 24900656 | 10.1021/ml300372f | Cynomolgus monkey | 8 |
| 24900656 | 10.1021/ml300372f | Mus musculus | 1 |
| 24900656 | 10.1021/ml300372f | Rattus norvegicus | 1 |
| 24900656 | 10.1021/ml300372f | Muscarinic acetylcholine receptor M5 | 1 |
| 24900656 | 10.1021/ml300372f | Muscarinic acetylcholine receptor M4 | 1 |
| 24900656 | 10.1021/ml300372f | Muscarinic acetylcholine receptor M3 | 1 |
| 24900656 | 10.1021/ml300372f | Muscarinic acetylcholine receptor M2 | 1 |
| 24900656 | 10.1021/ml300372f | Muscarinic acetylcholine receptor M1 | 1 |
Data from ChEMBL 36 via Core Engine