Compound Detail
CHEMBL2336193
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL2336193 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VOVVFGVLXRWVBR-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
368.4
MW (Da)
5.12
ALogP
4
HBA
2
HBD
58.2
PSA (Ų)
0.67
QED
1
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.62
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Trypanosoma brucei rhodesiense CHEMBL612348 | IC50 | 4.62 | 4.62 | 24000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Trypanosoma brucei rhodesiense | IC50 | = | 24000.0 | nM | 4.62 | Antitrypanosomal activity against Trypanosoma brucei rhodesiense after 48 hrs by... | 23337598 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 23337598 | 10.1016/j.bmcl.2012.12.075 | L6 | 1 |
| 23337598 | 10.1016/j.bmcl.2012.12.075 | Trypanosoma brucei rhodesiense | 1 |
Data from ChEMBL 36 via Core Engine