Compound Detail
CHEMBL234175
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL234175 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RIUIINZHASNDFH-UZYVYHOESA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
390.6
MW (Da)
5.81
ALogP
4
HBA
0
HBD
15.6
PSA (Ų)
0.56
QED
1
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 8.3
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cannabinoid receptor 2 CHEMBL253 | Ki | 8.3 | 8.3 | 5.0 | 1 |
| Cannabinoid receptor 1 CHEMBL218 | Ki | 6.61 | 6.61 | 243.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cannabinoid receptor 2 | Ki | = | 5.0 | nM | 8.3 | Binding affinity to human CB2 receptor | 17531479 |
| Cannabinoid receptor 1 | Ki | = | 243.0 | nM | 6.61 | Binding affinity to human CB1 receptor | 17531479 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17531479 | 10.1016/j.bmcl.2007.04.099 | Cannabinoid receptor 2 | 1 |
| 17531479 | 10.1016/j.bmcl.2007.04.099 | Cannabinoid receptor 1 | 1 |
Data from ChEMBL 36 via Core Engine