Compound Detail
CHEMBL23642
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Basic Information
| ChEMBL ID | CHEMBL23642 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | AQPSJZHJFAQTGQ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
348.5
MW (Da)
4.59
ALogP
6
HBA
1
HBD
54.2
PSA (Ų)
0.62
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 4.76
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Oryctolagus cuniculus CHEMBL374 | EC50 | 4.76 | 4.76 | 17300.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Oryctolagus cuniculus | EC50 | = | 17300.0 | nM | 4.76 | In vitro contraction of rabbit aorta strips. | 7837222 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 7837222 | 10.1021/jm00001a017 | Oryctolagus cuniculus | 2 |
| 7837222 | 10.1021/jm00001a017 | Voltage-dependent L-type calcium channel subunit alpha-1C | 1 |
Data from ChEMBL 36 via Core Engine