Compound Detail
CHEMBL2367824
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Basic Information
| ChEMBL ID | CHEMBL2367824 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PDCLPGSYMZLLDX-MRVPVSSYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
195.3
MW (Da)
1.59
ALogP
3
HBA
1
HBD
44.5
PSA (Ų)
0.79
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 1 meas. best 5.56
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Serotonin (5-HT) receptor CHEMBL2094123 | Kd | 5.56 | 5.56 | 2754.2 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Serotonin (5-HT) receptor | Kd | = | 2754.23 | nM | 5.56 | Affinity against 5-hydroxytryptamine receptors in rat fundus model | 7365744 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 7365744 | 10.1021/jm00177a017 | Serotonin (5-HT) receptor | 1 |
| 10956215 | 10.1021/jm9906062 | 5-hydroxytryptamine receptor 2A | 1 |
| 10956215 | 10.1021/jm9906062 | 5-hydroxytryptamine receptor 2C | 1 |
Data from ChEMBL 36 via Core Engine