Compound Detail
CHEMBL2369787
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)/C=C\c1ccc(OC)cc1
Basic Information
| ChEMBL ID | CHEMBL2369787 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HXFNFYNLVICVMK-KEYNBIDKSA-N |
1
Targets
2
Activities
2
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
1008.2
MW (Da)
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 1 meas. best 7.22
Ki 1 meas. best 8.85
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Lutropin-choriogonadotropic hormone receptor CHEMBL2456 | Ki | 8.85 | 8.85 | 1.4 | 1 |
| Lutropin-choriogonadotropic hormone receptor CHEMBL2456 | Kd | 7.22 | 7.22 | 60.3 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Lutropin-choriogonadotropic hormone receptor | Ki | = | 1.413 | nM | 8.85 | In vitro binding affinity for Luteinizing hormone releasing hormone receptor fro... | 2552116 |
| Lutropin-choriogonadotropic hormone receptor | Kd | = | 60.26 | nM | 7.22 | In vivo inhibition of leutenising hormone in rats. | 2552116 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 2552116 | 10.1021/jm00130a019 | Lutropin-choriogonadotropic hormone receptor | 2 |
Data from ChEMBL 36 via Core Engine