Compound Detail
CHEMBL2370975
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CC(C)Oc1ccc(C[C@@H]2NC(=O)CC3(CCCCC3)SSC[C@@H](C(=O)N3CCC[C@H]3C(=O)N[C@H](CCCN=C(N)N)C(=O)NCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1
Basic Information
| ChEMBL ID | CHEMBL2370975 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FYLOFHFZLGTUHI-ZXMMRKAHSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
1150.4
MW (Da)
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 2 meas. best 8.19
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Rattus norvegicus CHEMBL376 | Kd | 8.19 | 7.85 | 6.5 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Rattus norvegicus | Kd | = | 6.457 | nM | 8.19 | In vivo pA2 value represent the negative logarithm of the effective dose divided... | 7086821 |
| Rattus norvegicus | Kd | = | 30.9 | nM | 7.51 | In vivo pA2 value represent the negative logarithm of the effective dose divided... | 7086821 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 7086821 | 10.1021/jm00343a009 | Rattus norvegicus | 4 |
Data from ChEMBL 36 via Core Engine